First Round 2nd session Question

I.      Buzzer Quiz

1.       State the afferent nerve for baroreceptor reflex from the carotid sinus.

n  AnswerGlossopharyngeal nerve


2.       What is the name of the junction which seals adjacent epithelial cells?

n  AnswerTight junction


3.       What is the name of the structure where pyramidal tract crosses to the opposite side?

n  AnswerMedulla (oblongata)


4.       What is the name of the layer of retina which constitutes sixth layer from the choroid side?

n  AnswerInner nuclear layer


5.       In which structure is the center of light reflex located?

n  AnswerMidbrain


6.       What is the name of the hormone whose secretion increases during non-REM sleeping one hour after falling asleep?

n  AnswerGrowth hormone(GH)


7.       Since free ion shows cytotoxicity, it binds with protein in blood. What is this protein called?

n  AnswerTransferrin


8.       What stage of cardiac cycle us shown as the period from A to B in the right figure?

n  AnswerIsovolumic contraction (phase)


9.       What is the name of the peptide hormone which is produced from granulosa cell by FSH and has negative feedback control to FSH formation in pituitary gland?

n  AnswerInhibin

n  CommentEstradiol is not correct because it is a steroid hormone.




10.    What is the name of the mechanism which controls muscle tonus by discharge of γ motor nerve fiber during exercise?

n  Answer:α-γ linkage


11.    Melanocytes synthesize melanin by activation of enzymes by UVB. What amino acid serves as substrate for melanin synthesis?

n  AnswerTyrosine


12.    What is the lesion in presbyopia?

n  Answer(crystalline) lens


13.    What activates chymotrypsinogen, procarboxypeptidase, proaminopeptidase contained in pancreatic juice?

n  AnswerTrypsin


14.    What is the tissue which secretes a component of external layer of tear film?

n  AnswerMeibom gland


15.    What is the name of exocrine mechanism for mammary gland?

n  AnswerApocrine secretion


16.    Which vitamin is not contained sufficiently both in human milk and regular milk and often cause insufficiency in neonates?

n  AnswerVitamin K


17.    Which coagulation factor makes fibrin polymer stable?

n  AnswerNo.ⅩⅢ coagulation factor


18.    Which ion flows into inner hair cell through mechanical-dependent channels by sound stimulation?

n  AnswerPotassium

n  CommentThere is an abundant potassium in endolymph of the inner ear, which helps us understand the mechanism of depolarization of inner hair cell.


19.    What abnormal formation is occurred to DNA by irradiating UV?

n  AnswerPyrimidine dimers

n  Commentpatient with xeroderma pigmentosum cannot fix this abnormal DNA chain.



20.    Macrophage uptakes oxidated LDL through Scavenger receptors. What is the name of macrophage which accumulates cholesterol?

n  AnswerFoam cell

n  CommentFoam cell and deposition of cholesterol to vascular wall induce secretion of inflammatory cytokines, which proliferates smooth muscle of tunica media and endothelium and creates plaque.



II.    Flip Quiz

1.       Arrange the visual pathway correctly from retina to primary visual area.

    Some of the following are not included in the pathway.

      Lateral geniculate body

      Optic nerve

      Oculomotor nerve

      Optic tract

      Optic radiation

      Edinger-Westphal nucleus

n  Answer:② → ④ → ① → ⑤


2.       Choose 3 of the following that are the target of protein kinase.









n  Answer:①・③・⑧










3.       Mention the changes in postmenopausal women comparing with before menopause.




      Bone density

n  Answer:① Decreased ② Increased ③ Increased ④ Decreased

n  Comment

FSH · LH tends to increase with the release of Feedback inhibition due to estrogen reduction.

Estrogen promotes expression of LDL receptor. Therefore, dyslipidemia tends to occur after menopause.


4.       State the substances which cause followingtogustation.

Ø  Acidic taste --- ( ① )

Ø  Salty taste --- Na+

Ø  Sweet taste --- ( ② )

Ø  Bitter taste --- Bitter substance

Ø  Umami --- ( ③ )

n  Answer:① H+ (acid)  ② Glucose  ③ Glutamate


5.       The following figure shows citric acid cycle. Fill up the blanksto. 【Picture is deleted

n  Answer: ① Oxaloacetate(Oxaloacetic acid)  ② α-ketoglutarate(α-ketoglutaric acid)

 Succinate(Succinic acid)


6.       Choose 3 of the following that rises in hyperthyroidism.

      Heart rate

      Diastolic blood pressure





n  Answer:①・③・⑥






III.Time Attack


1.       Increase in extracellular fluid can be caused by decrease in serum albumin.

n  AnswerTrue


2.       mRNA maturation requires removal of exons bySplicing

n  AnswerFalse


3.       Capillary vessels are the main components of vascular resistance.

n  AnswerFalse


4.       Injection of heparin can cause bleeding tendency.

n  AnswerTrue


5.       At the time of urination the pontine micturition center (PMC) excites the Onuf nucleus in the spinal cord.

n  AnswerFalse


6.       Respiratory failure with 65 mmHg of PaCO2 is type I.

n  AnswerFalse


7.       Which of the following substances is not produced from tyrosine?

P)     Dopamine

Q)    Adrenaline

R)     Melanin

S)      Serotonin

n  AnswerS







8.       In which phase of action potential will the electrolyte that binds troponin flow into the cardiac muscle?

P)     Phase0

Q)    Phase1

R)     Phase2

S)      Phase3

n  AnswerR


9.       Which is the cell that makes up the myelin sheath of the peripheral nervous system?

P)     Schwann cell

Q)    Ependymal cell

R)     Microglia

S)      Oligodendroglia

n  AnswerP


10.    Which of the following structuresdisorder is the cause of cataract?

P)     Crystalline lens

Q)    Cornea

R)     Ciliary body

S)      Vitreous body

n  AnswerP


11.    Which of the following medicines reinforces the effect of incretin?

P)     Biguanide

Q)    DPP-4 inhibitor

R)     Thiazolidinedione

S)      Sulfonylurea compound

n  Answer:Q


12.    Which of the following nerves conducts gustation from the posterior 1/3 of the tongue?

P)     Hypoglossal nerve

Q)    Lingual nerve

R)     Glossopharyngeal nerve

S)      Cord of tympanum

n  AnswerR





13.    Which of the following anterior pituitary hormones increases due to disorder of hypothalamus?

P)     GH

Q)    TSH

R)     ACTH

S)      PRL

n  AnswerS


14.    What are the luxury goods considered to be a risk factor for COPD?

n  AnswerSmoking (cigarette)


15.    What is the enzyme that converts lactic acid and pyruvic acid?

n  AnswerLactate dehydrogenase (lactate dehydrogenase: LDH)


16.    What is the dendritic cell present in the skin tissue?

n  AnswerLangerhans cell


17.    What is the name of the system that conducts the action potential generated in the sinoatrial node to the whole myocardium?

n  Answer(excitatory and) conductive system


18.    What is the neurotransmitter of sympathetic preganglionic fibers?

n  Answeracetylcholine


19.    What is the vitamin which is deficient in rickets?

n  AnswerVitamin D


20.    What is the ligand that binds to and activates the receptor?

n  Answeragonist




1.       The half-life of albumin is approximately 20 days.

n  AnswerTrue


2.       Insulin is synthesized in the liver.

n  AnswerFalse


3.       The first heart sound is composed of the closure of atrioventricular valves.

n  AnswerTrue


4.       The oxygen dissociation curve of hemoglobin draws an S-shaped curve.

n  AnswerTrue


5.       Chronic renal failure generally results in metabolic acidosis.

n  AnswerTrue

n  CommentIn chronic renal failure, the discharge of hydrogen ions into urine will not function normally, so it will be metabolic acidosis.


6.       Romberg signs is positive with cerebellar ataxia.

n  AnswerFalse


7.       Which metabolic pathway is promoted by insulin?

P)     Fatty acid synthesis

Q)    Glycogenolysis

R)     Gluconeogenesis

S)      Lipolysis

n  AnswerP


8.       Which of the following blood vessels branches directly from the aorta?

P)     Splenic artery

Q)    Gastroepiploic artery

R)     Superior mesenteric artery

S)      Internal iliac artery

n  AnswerR


9.       Which cranial nerve does not pass through the superior orbital fissure?

P)     Optic nerve

Q)    Oculomotor nerve

R)     Trochlear nerve

S)      Abducent nerve

n  AnswerP





10.    Which of the following combines with intracellular free Ca?

P)     Myosin

Q)    Troponin C

R)     Actin

S)      Tropomyosin

n  Answer: Q


11.    Which of the following substances produced in lungs has vasoconstrictive action?

P)     Endothelin

Q)    NO

R)     Prostacyclin

S)      Histamine

n  Answer: P


12.    Which of the following nucleus contains cholinergic nerve fiber?

P)     Globus pallidus

Q)    Basal nucleus of Meynert

R)     Locus ceruleus

S)      Substantia nigra

n  Answer: Q

n  CommentGlobus pallidus: GABA/ Locus ceruleus: noradrenalin/ Substantia nigra: Dopamine


13.    Which of the following diseases causes elevation of serum TSH?

P)     Basedow disease

Q)    Subacute thyroiditis

R)     Plummer disease

S)      Chronic thyroiditis

n  Answer: S


14.    What are the cells that produce acid through bone resorption?

n  AnswerOsteoclast


15.    What is the neurotransmitter of α motor neurons?

n  Answeracetylcholine


16.    What substances are regenerated in the Roman reaction in skeletal muscle?

n  AnswerATP


17.    What is the name of the valve between the left atrium and the left ventricle?

n  AnswerMitral valve


18.    What is the neurotransmitter of projection fibers from the substantia nigra to the striatum?

n  AnswerDopamine


19.    What is the hormone secreted from the globular zone of the adrenal cortex?

n  AnswerAldosterone


20.    Complement or antibody promotes phagocytosis. What is this effect called?

n  AnswerOpsonization action




1.       The concentration of extracellular Magnesium is higher than that of intracellular.

n  AnswerFalse


2.       Vitamin E is lipid soluble.

n  AnswerTrue


3.       Atrioventricular valves close during isovolumetric contraction.

n  AnswerTrue


4.       Meissner corpuscle senses pain.

n  AnswerFalse


5.       If Factor VII activity decreases, PT is normal but APTT is prolonged.

n  AnswerFalse


6.       Metabolic acidosis manifests in Fanconi syndrome.

n  AnswerTrue







7.       Which vitamin is water- soluble?

P)     Vitamin A

Q)    Vitamin C

R)     Vitamin E

S)      Vitamin K

n  AnswerQ


8.       Which of the following cells secretes cholecystokinin?

P)     I cell

Q)    M cell

R)     B cell

S)      C cell

n  AnswerP


9.       Which cranial nerves is not related to eye movements?

P)     Oculomotor nerve

Q)    Trigeminal nerve

R)     Abducent nerve

S)      Trochlear nerve

n  AnswerQ


10.    Which of the following is released from vascular endothelial cells and causes vasoconstriction?

P)     Noradrenaline

Q)    PCI2

R)     Serotonin

S)      Endothelin

n  Answer: S


11.    Which of the following breath sounds is heard when alveolus which reduction of compliance makes the alveolus wall hard?

P)     Coarse crackle

Q)    Fine crackle

R)     Rhonchi

S)      Wheezes

n  Answer: Q




12.    Which of the following regions doesnt compose pyramidal tract?

P)     Internal capsule

Q)    Globus pallidus

R)     Spinal cord

S)      Cerebral peduncle

n  Answer: Q


13.    Which of the following substances is released from fat cell and inhibits fibrinolytic system?

P)     Leptin

Q)    Adiponectin

R)     TNF-α

S)      PAI-1

n  AnswerS


14.    What is the dominant nerve of the major psoas muscle?

n  AnswerFemoral nerve


15.    How many percent of NaCl is included in the physiological saline solution used for humans?

n  Answer0.9%


16.    What is the substrate for GABA synthesis?

n  AnswerGlutamic acid


17.    Which cells act as NK cells in the sinusoids?

n  AnswerPit cell


18.    What is the hole in the atrial septum at fetal stage?

n  AnswerForamen ovale


19.    Which organ produces erythropoietin?

n  Answerkidney


20.    A stop codon inserted by DNA sequence mutation is called?

n  AnswerNonsense mutation





1.       Acetylcholine receptors at neuromuscular junctions are muscarinic.

n  AnswerFalse


2.       SRY gene is necessary for sexual development to be male.

n  AnswerTrue


3.       Peyers patches are mainly found in the duodenum.

n  AnswerFalse


4.       The blind spots of Mariotte are located at ear sides in the visual fields.

n  AnswerTrue

n  CommentThe blind spot of Mariotte is small portion of the visual field of each eye that corresponds to the position of the optic disk within the retina. The blind spot of the eye is located to the ear side of the center of vision because the optic disk is located at the nasal side within the retina.


5.       Fibrinogen is directly activated by Factor X.

n  AnswerFalse

n  CommentFibrinogen is directly activated by thrombin.


6.       Total excision of the stomach causes iron deficiency anemia.

n  AnswerTrue


7.       Which of the following lipoproteins has the largest proportion of TG among the constituents?

P)     VLDL

Q)    LDL

R)     Chiromicron

S)      IDL

n  AnswerR


8.       Which of the following protects the stomach?

P)     Gastrin

Q)    Histamine

R)     Insulin

S)      Prostaglandin

n  AnswerS


9.       Which is the correct action of oxytocin?

P)     Promotion of dopamine secretion

Q)    Suppression of the uterine smooth muscle contraction

R)     Milk ejection

S)      Promotion of lactation

n  AnswerR


10.    Which of the following vessels contains blood with lowest oxygen partial pressure in fetal circulation?

P)     Umbilical vein

Q)    venous duct

R)     Arterial duct

S)      Umbilical artery

n  Answer: S


11.    Which of the following is diagnosed when the patients vital capacity is 70% and the FEV1 is 90%?

P)     Obstructive defect

Q)    Mixed defect

R)     Restrictive defect

S)      Normal

n  Answer: R


12.    Which of the following reflection is normal reflex in infant at 11 months after birth?

P)     Sucking reflex

Q)    Moro reflex

R)     Palm grasp reflex

S)      Babinski reflex

n  Answer:S

n  CommentBabinski reflex is normal in infant at 2 years after birth because of undevelopment of pyramidal tract.


13.    Which of the following hemoglobin appears in a patient with at sickle cell disease?

P)     HbA

Q)    HbF

R)     HbS

S)      HbH

n  AnswerR



14.    What are the major antagonistic muscles in patellar tendon reflex?

n  AnswerFemoral biceps (hamstring)


15.    What is the complex of porphyrin ring and iron?

n  AnswerHeme


16.    What is the surface antibody of B cells produced in the primary immune response?

n  AnswerIgM


17.    What is the gastrointestinal hormone that promotes the secretion of pancreatic enzymes?

n  AnswerCholecystokinin (CCK)


18.    What is the nerve being impaired in the patient who cannot dorsalize the hand?

n  AnswerRadial nerve


19.    What are the cell components of blood derived from megakaryocytes?

n  Answerplatelet


20.    What is called a glycosaminoglycan bound to the core protein?

n  AnswerProteoglycan




1.       Albumin is the main substance maintaining intravascular osmotic pressure.

n  AnswerFalse

n  CommentIntravascular osmotic pressure is mainly maintained by sodium ions.


2.       At the time of starvation, the brain uses fatty acid as an energy substrate in addition to sugar.

n  AnswerFalse

n  CommentFatty acids cannot cross the blood brain barrier. For this reason, the brain uses ketone bodies during starvation.


3.       The pancreas is a retroperitoneal organ.

n  AnswerTrue


4.       Rod cells are related to sensation of colors.

n  AnswerFalse

5.       It is difficult for a patient with subthalamic nuclear disorder to start and stop the motion smoothly.

n  AnswerTrue


6.       Beta blockers are effective for the prevention of coronary vasospastic angina.

n  AnswerFalse


7.       Which organ is peripheral lymphoid organ?

P)     Spleen

Q)    Thymus

R)     Bone marrow

S)      Skeletal muscle

n  AnswerP


8.       Which of the following muscles does not participate in respiratory movement?

P)     Platysma muscle

Q)    External intercostal muscle

R)     Diaphragm

S)      Internal intercostal muscle

n  AnswerP


9.       Which hormone is secreted from the posterior pituitary gland?

P)     ACTH

Q)    ADH

R)     PRL

S)      FSH

n  AnswerQ


10.    Which of the following ovarian follicle has zona pellucida for the first time?

P)     Primordial follicle

Q)    Primary follicle

R)     Secondary follicle

S)      Mature follicle

n  AnswerQ






11.    Which of the following symptoms develops at the earliest in a patient with dementia of Alzheimer?

P)     Memory disturbance

Q)    Executive function disorders

R)     Parkinsonism

S)      Constructional apraxia

n  AnswerP

n  CommentMemory disturbance isnt remarkable at dementia with Lewy bodies and vascular dementia


12.    Which of the following channels participates in action potential phase 1 of ordinary cardiac muscle?

P)     Voltage-dependent K channel

Q)    Voltage-dependent Na channel

R)     Voltage-dependent Ca channel

S)      Ligand-dependent Na channel

n  Answer: P


13.    Which of the following pathophysiological condition is caused by renovascular hypertension?

P)     Secondary hyperthyroidism

Q)    Secondary aldosteronism

R)     Increase of adrenalin in blood

S)      Cushing syndrome

n  Answer: Q


14.    How many human cervical vertebrae do you have?

n  Answer7


15.    What is the metabolic system that exists in the liver and detoxifies ammonia?

n  AnswerUrea cycle


16.    What is the structure in which deoxyribose or ribose is N-glycosidically bound to a base called?

n  AnswerNucleoside


17.    Which organ produces angiotensinogen?

n  AnswerLiver


18.    What is the cell which secretes surfactant in the lung?

n  AnswerType II alveolar epithelial cells



19.    What is the vitamin which is deficient in Wernicke's encephalopathy?

n  AnswerVitamin B1


20.    Which organ mainly produces thrombopoietin (TPO)?

n  AnswerLiver